Start Sedating antihistamines examples

Sedating antihistamines examples

The H1 block is useful to treat allergic reactions.

An initial burst of mediator activity will often set a series of cell responses in motion which will amplify and prolong disturbances.

The sedating group act on brain H1 receptors where they cause sedative effects, a dangerous effect if you are driving, operating machinery, or otherwise need to be alert and vigilant.

Antihistamine sedative effects are increased by concurrent alcoholic beverage ingestion and by a long list of psychotropic drugs.

Although they are undoubtedly effective to certain extent, some aspects of their psychopharmacology have to be resolved; for example, there is poor evidence of pharmacodynamics in humans, problematic efficacy evaluation in clinical studies, as well as cumbersome production of standardized extracts and lack of bioequivalence between different extracts.